1073163-35-5

Basic information

• Product Name: ethyl 2-diazo-3-(4-methoxyphenyl)-3-oxopropanoate
• Synonyms: ethyl 2-diazo-3-(4-methoxyphenyl)-3-oxopropanoate
• CAS NO: 1073163-35-5
• Molecular Weight: 248.238
• Mol File: 1073163-35-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: ethyl 2-diazo-3-(4-methoxyphenyl)-3-oxopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-diazo-3-(4-methoxyphenyl)-3-oxopropanoate(1073163-35-5)
• EPA Substance Registry System: ethyl 2-diazo-3-(4-methoxyphenyl)-3-oxopropanoate(1073163-35-5)

Safety Data

• Hazardous Substances Data: 1073163-35-5(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 123-11-5 4-methoxy-benzaldehyde 
• 39910-24-2 ethyl-3-hydroxy-2-diazo-3-(4-methoxyphenyl)-propanoate 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 4231-69-0 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole 

Downstream Products

• 29113-70-0 ethyl 2-(4-methoxyphenyl)-5-phenylfuran-3-carboxylate 
• 1287721-31-6 methyl 2-{(2-ethoxy-1-(4-methoxybenzoyl)-2-oxoethyl)[(2,2,2-trichloroethoxy)carbonyl]amino}-3-(phenylthio)acrylate 
• 40140-16-7 ethyl (p-methoxyphenyl)oxoacetate 

Relevant articles and documents

Synthesis and use of a cost-effective, aqueous soluble diazo transfer reagent – m-carboxybenzenesulfonyl azide

Herein, we report the preparation and use of m-carboxybenzenesulfonyl azide as a diazo transfer reagent. This compound is an inexpensive and potentially scalable alternative to many of the diazo transfer reagents currently available, most of which have hazards associated with their use. Its usefulness and suitability as a diazo transfer reagent was assessed on the basis of cost, safety and its effectiveness in diazo transfer to a variety of different substrates.

Sulfur-controlled and rhodium-catalyzed formal (3 + 3) transannulation of thioacyl carbenes with alk-2-enals and mechanistic insights

A rhodium-catalyzed denitrogenative formal (3 + 3) transannulation of 1,2,3-thiadiazoles with alk-2-enals is achieved, producing 2,3-dihydrothiopyran-4-ones in moderate to excellent yields. An inverse KIE of 0.49 is obtained, suggesting the reversibility of the oxidative addition of thioacyl Rh(i) carbenes to alk-2-enals. The late-stage structural modifications of steroid compounds are realized. Moreover, our studies show that thioacyl carbenes have different reactivities to those of α-oxo and α-imino carbenes, and highlight the importance of heteroatoms in deciding the reactivities of heterovinyl carbenes.

Oxazolinyl-Assisted Ru(II)-Catalyzed C?H Functionalization Based on Carbene Migratory Insertion: A One-Pot Three-Component Cascade Cyclization

A rare, ruthenium-catalyzed, oxazolinlyl assisted C?H functionalization and three-component cascade cyclization for the synthesis of isoquinolinones via a metal-carbene migratory insertion is reported. The transformation is unique since it involves the fo