107327-31-1

Basic information

• Product Name: N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene
• Synonyms: N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene
• CAS NO: 107327-31-1
• Molecular Weight: 295.446
• Mol File: 107327-31-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene(107327-31-1)
• EPA Substance Registry System: N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene(107327-31-1)

Safety Data

• Hazardous Substances Data: 107327-31-1(Hazardous Substances Data)

Upstream product

• 819-79-4 diisopropylamine hydrochloride 
• 107327-36-6 1-(1-piperidinyl)-2-(methylsulfonyl)-3-phenyl-2-propene 
• 107327-29-7 1-chloro-1-phenyl-2-(methylsulfonyl)propane 
• 54845-43-1 2-(methylsulfonyl)-1-phenyl-1-propene 
• 637-50-3 1-phenylpropene 
• 107327-30-0 3-bromo-2-(methylsulfonyl)-1-phenyl-1-propene 
• 108-18-9 diisopropylamine 

Downstream Products

• 107327-36-6 1-(1-piperidinyl)-2-(methylsulfonyl)-3-phenyl-2-propene 
• 819-79-4 diisopropylamine hydrochloride 

Relevant articles and documents

Synthesis and Reactivity of N-Substituted-1-amino-2-(methylsulfonyl)-3-phenyl-2-propenes

The synthesis of 3-bromo-2-(methylsulfonyl)-1-phenyl-1-propene (1b) is described.Reaction of the allyl bromide 1b with tert-butylamine, diisopropylamine, glycine methyl ester, and piperidine in benzene solution yielded mixtures of direct substitution (SN2) and substitution-rearrangement (SN2') products, 2 and 3, respectively.The SN2:SN2' ratio ranged from 1:4 for reaction of 1b with glycine methyl ester to greater than 20:1 for the reaction with diisopropylamine.Amine hydrochloride promoted amine exchange reactions of N,N-diisopropyl-1-amino-2-(methylsulfonyl)-3-phenyl-2-propene (2a) and the amine exchange and aminotropic rearrangement reactions of the thermodynamically less stable N-tert-butyl-1-amino-2-(methylsulfonyl)-1-phenyl-2-propene (3b) are described.Evidence for acid-catalyzed aminotropic rearrangement and amine exchange reactions (3-->2) is presented.Equilibrium constants for reactions of 2a and of 2b with piperidine hydrochloride in chloroform solution were determined.