107389-18-4Relevant articles and documents
Zur protonenkatalysierten elktrophilen Substitution von 2,3-Dimethylindol mit Arylaldehyden: C6-Regioselektivitaet am Indol-Geruest
Schiffl, E.,Pindur, U.
, p. 651 - 656 (2007/10/02)
The proton catalyzed reaction of 2,3-dimethylindole (1) with several arylaldehydes 2 yields the 6,6'-bisindolylarylmethanes 5 regioselectively.No mechanistic information about the predominant attack of the aldehydes on the indole nucleus is obtained, because the reaction proceeds too fast to control.The electronrich aldehydes, 2,4,6-trimethoxybenzaldehyde and indole-3-carbaldehyde, yield exclusively the 6,6',6''-trisindolylmethane 9.The constitutions of all isolated methanes were elucidated by 400 MHz 1H-nmr spectroscopy.
