1075198-30-9

Basic information

• Product Name: COMU
• Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate;1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate;(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.);COMU(R) 97%;elagolix intermediate 13;COMU 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
• CAS NO: 1075198-30-9
• Molecular Formula: C12H19F6N4O4P
• Molecular Weight: 428.2678402
• EINECS: 1592732-453-0
• Mol File: 1075198-30-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: ca 160℃
• Appearance: White to pale yellow/Powder or Solid
• Storage Temp.: 2-8°C
• Solubility: Soluble in DMF 1mmol in 2mL.
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: COMU(CAS DataBase Reference)
• NIST Chemistry Reference: COMU(1075198-30-9)
• EPA Substance Registry System: COMU(1075198-30-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 1075198-30-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1075198-30-9 differently. You can refer to the following data:
1. (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholinocarbenium hexafluorophosphate is used as a coupling reagent in the peptide synthesis. It is suitable for solution phase & solid phase peptide synthesis, visual or colorimetric reaction monitoring possible.
2. COMU – Safer and More Efficient Peptide Coupling ReagentAdvantagesEqual or even superior performance to HATUNon-explosive (does not contain benzotriazole moiety)Suitable for solution phase & solid phase peptide synthesisUtmost retention of configuration – low to non-existent racemizationHigh solubility and stability in typical solventsVisual or colorimetric reaction monitoring possibleEasy removal of water-soluble by-products

General Description

This product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention".