1075254-10-2Relevant articles and documents
Efficient synthesis of 6-aryl-12H-pyrido-[2',3':4,5]pyrimido [1,2-a][1,8]naphthyridin-12-ones under microwave irradiation
Mogilaiah,Anitha,Vidya,Reddy, N. Vasudeva
, p. 2071 - 2073 (2008/09/18)
A straightforward and highly efficient procedure has been described for the synthesis of 6-aryl-12H-pyrido[2',3':4,5]-pyrimido[1,2-a][1,8]naphthyridin-12- ones 3 by the reaction of 3-aryl-2-chloro-1,8-naphthyridines 1 with 2-aminonicotinic acid 2 in glacial acetic acid under microwave irradiation. The products are obtained in very good yields and in a state of high purity. The structural assignments of compounds 3 were based on their elemental analyses and spectral (IR and 1H NMR) data.