107667-60-7 Usage
Description
Polaprezinc is a complex of zinc ion and L-carnosine, which serves as an antiulcer agent. It is effective in promoting the healing of gastric ulcers and preventing ulcer relapse. Polaprezinc is also known for its in vivo antioxidative properties, which contribute to its protective effect against gastric mucosal injury. Additionally, it has been found to be an activator of bone formation and has an inhibitory effect on bone resorption, making it potentially useful in the treatment of osteoporosis. Furthermore, Polaprezinc has been considered for the prophylaxis and treatment of alcoholic hepatopathy, viral hepatitis, or other hepatopathies caused by certain drugs, poisons, and radiation. It is a white to pale-yellow crystalline solid and is available under the brand name Promac.
Uses
Used in Pharmaceutical Industry:
Polaprezinc is used as an anti-gastric ulcer agent for promoting the healing of gastric ulcers and preventing ulcer relapse.
Used in Dietary Supplements Industry:
Polaprezinc is used as a new dietary supplement for its anti-ulcer and antioxidative properties. It is available under the brand name PepZinGI(R) and is approved by the federal agency.
Used in Orthopedics:
Polaprezinc is used as a potential treatment for osteoporosis due to its ability to activate bone formation and inhibit bone resorption, thus preventing the deterioration of bone metabolism.
Used in Hepatology:
Polaprezinc is used for the prophylaxis and treatment of alcoholic hepatopathy, viral hepatitis, or other hepatopathies caused by certain drugs, poisons, and radiation.
Originator
Hamari Chemicals (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 107667-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,6,6 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 107667-60:
(8*1)+(7*0)+(6*7)+(5*6)+(4*6)+(3*7)+(2*6)+(1*0)=137
137 % 10 = 7
So 107667-60-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N4O3.Zn/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6;/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16);/q;+2
107667-60-7Relevant articles and documents
Methods for producing L-carnosine zinc complex
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Paragraph 0021; 0022, (2017/06/20)
Disclosed is a method for conveniently synthesizing, at high purity and high yield, a crystalline L-carnosine zinc complex which is useful as an antiulcer treatment agent without having a separate refining step. A method for producing an L-carnosine zinc complex comprises the steps of: suspending L-carnosine and zinc salts in an alcohol or a water-containing alcohol; producing an alkali metal compound solution by dissolving an alkali metal compound in an alcohol or a water-containing alcohol; precipitating an L-carnosine zinc complex by adding the alkali metal compound solution in a suspension of the L-carnosine and the zinc salts; adding refined water in a reactive liquid including the L-carnosine zinc complex; and filtering an L-carnosine zinc complex crystal.COPYRIGHT KIPO 2017