107785-25-1

Basic information

• Product Name: 1-benzyl-4-(phenylsulfonyl)piperazine
• Synonyms: 1-benzyl-4-(phenylsulfonyl)piperazine
• CAS NO: 107785-25-1
• Molecular Formula: C₁₇H₂₀N₂O₂S
• Molecular Weight: 316.4179
• Mol File: 107785-25-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-benzyl-4-(phenylsulfonyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-(phenylsulfonyl)piperazine(107785-25-1)
• EPA Substance Registry System: 1-benzyl-4-(phenylsulfonyl)piperazine(107785-25-1)

Safety Data

• Hazardous Substances Data: 107785-25-1(Hazardous Substances Data)

Upstream product

• 2759-28-6 1-phenylmethylpiperazine 
• 873-55-2 sodium benzenesulfonate 
• 57260-70-5 4-benzyl-piperazine-1-carboxylic acid tert-butyl ester 
• 16728-92-0 N-benzyl-N,N-bis(cyanomethyl)amine 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 2759-28-6 1-phenylmethylpiperazine 

Relevant articles and documents

PTAB mediated open air synthesis of sulfonamides, thiosulfonates and symmetrical disulfanes

A facile methodology has been described which has successfully simplified the generation of sulfonamides, thiosulfonates and symmetric disulfanes. This “trio” of reactions occur in an open air metal free atmosphere and has also been scaled up to grams making it suitable for commercialization. The reactions also have been successfully carried out with asymmetric variants, thus contributing to the chiral pool. The user friendly “trio” enables easy generation of these versatile sulfur analogues and the reaction condition employed depict an economic outline.

Design, synthesis and antimalarial activity of benzene and isoquinoline sulfonamide derivatives

A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for an