1078151-50-4

Basic information

• Product Name: ethyl 4-(benzyloxy)-1-(3-chloroallyl)-7-iodo-1H-indole-2-carboxylate
• Synonyms: ethyl 4-(benzyloxy)-1-(3-chloroallyl)-7-iodo-1H-indole-2-carboxylate
• CAS NO: 1078151-50-4
• Molecular Weight: 495.744
• Mol File: 1078151-50-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-(benzyloxy)-1-(3-chloroallyl)-7-iodo-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(benzyloxy)-1-(3-chloroallyl)-7-iodo-1H-indole-2-carboxylate(1078151-50-4)
• EPA Substance Registry System: ethyl 4-(benzyloxy)-1-(3-chloroallyl)-7-iodo-1H-indole-2-carboxylate(1078151-50-4)

Safety Data

• Hazardous Substances Data: 1078151-50-4(Hazardous Substances Data)

Upstream product

• 922506-90-9 ethyl 4-(benzyloxy)-7-iodo-1H-indole-2-carboxylate 
• 542-75-6 E/Z-1,3-Dichloropropene 

Downstream Products

• 1078151-51-5 ethyl 8-benzyloxy-5-(chloromethyl)-4,5-dihydro-1H-pyrrolo[3,2,1-hi]indoline-2-carboxylate 

Relevant articles and documents

A facile rearrangement of pyrroloindoline derivative to pyrroloquinoline: A new analogues of duocarmycins

(Chemical Equation Presented) Free-radical generated at C-7 position of indole derivative bearing N-(3′-chloroallyl) group prompted a regioselective intramolecular cyclization to furnish pyrroloindoline derivative, through the more favorable 5-exo-trig cyclization mode. The pyrroloindoline compound smoothly rearranged to pyrroloquinoline under mild conditions.