1079649-91-4

Basic information

• Product Name: 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one
• CAS NO: 1079649-91-4
• Molecular Weight: 209.205
• Mol File: 1079649-91-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one(1079649-91-4)
• EPA Substance Registry System: 2,4-dihydroxy-6-isopropyl-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one(1079649-91-4)

Safety Data

• Hazardous Substances Data: 1079649-91-4(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 6341-93-1 orotic acid 
• 75-31-0 isopropylamine 
• 4156-75-6 2,4-dihydroxyfuro[3,4-d]pyrimidin-7(5H)-one 
• 15572-56-2 isopropylamine hydrochloride 
• 65-86-1 orotic acid 

Downstream Products

• 1079649-94-7 2,4-dichloro-6-isopropyl-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079664-08-6 C₂₂H₂₈N₆O₂ 
• 1079664-02-0 C₂₃H₃₀N₆O₂ 
• 1079653-89-6 C₂₃H₂₉ClN₆O₂ 
• 1079653-92-1 C₂₄H₃₂N₆O₂ 
• 1079653-27-2 C₂₄H₃₁ClN₆O₂ 
• 1079653-48-7 C₂₅H₃₃ClN₆O₂ 
• 1079653-46-5 C₂₆H₃₃ClN₆O₂ 
• 1079654-39-9 C₂₅H₃₃ClN₆O₂ 
• 1079655-25-6 2-(4-acetyl-piperazin-1-yl)-4-(4-chloro-benzylamino)-6-isopropyl-5,6-dihydro-pyrrolo[3,4-d]-pyrimidin-7-one 
• 1079657-75-2 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-(4-(trifluoromethyl)benzylamino)-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079653-74-9 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-{[4-(trifluoromethoxy)benzyl]amino}-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 
• 1079657-78-5 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-(2-methoxy-4-(trifluoromethoxy)benzylamino)-5H-pyrrolo[3,4-d]pyrimidin-7(6H)-one 
• 1079653-78-3 2-(4-acetylpiperazin-1-yl)-6-isopropyl-4-{[(1R)-1-(4-methylphenyl)ethyl]amino}-5,6-dihydro-7H-pyrrolo[3,4-d]pyrimidin-7-one 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS AS KCC2

The invention concerns compounds of Formula (I): (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and ring A have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KCC2 mediated diseases.

PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

Compounds of formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, R3, R4, and R5 and are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.