108-82-7 Usage
Description
Diisobutylcarbinol, also known as 2,6-Dimethyl-4-heptanol, is a colorless liquid with a clear chemical composition. It has a flash point of 162°F, is less dense than water, and is insoluble in water. Its vapors are heavier than air, and it has an aroma threshold value of 1.3 ppm for detection.
Uses
Used in Fragrance Industry:
Diisobutylcarbinol is used as a fragrance ingredient due to its distinct aroma properties.
Used in Chemical Synthesis:
Diisobutylcarbinol is used in the preparation of protected β-hydroxybutyrates, which are important intermediates in organic synthesis.
Used in Dynamic Kinetic Resolution (DKR):
Diisobutylcarbinol serves as a hydrogen donor during the dynamic kinetic resolution (DKR) of various diols, monoprotected diols, and protected hydroxy aldehydes, facilitating the synthesis of enantiomerically pure compounds.
Occurrence:
Diisobutylcarbinol has been reported to be found in cognac, white wine, and red wine, indicating its natural presence in these beverages.
Preparation
By catalytic hydrogenation of diisobutyl ketone
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Diisobutylcarbinol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Health Hazard
None expected
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Chemical Reactivity
Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Safety Profile
Moderately toxic by
ingestion and intraperitoneal routes. Mddly
toxic by skin contact. A powerful systemic
irritant by inhalation. A skin and eye irritant.
Can cause central nervous system and liver
damage when ingested. Combustible when
exposed to heat or flame; can react with
oxidizing materials. To fight fire, use alcohol
foam, foam, CO2, dry chemical. When
heated to decomposition it emits acrid
smoke and fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 108-82-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 108-82:
(5*1)+(4*0)+(3*8)+(2*8)+(1*2)=47
47 % 10 = 7
So 108-82-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H20O/c1-7(2)5-9(10)6-8(3)4/h7-10H,5-6H2,1-4H3
108-82-7Relevant articles and documents
-
Cox,Adkins
, p. 3364,3369 (1939)
-
Hubbard,Brown
, p. 676 (1978)
Multiple Halogenation of Aliphatic C?H Bonds within the Hofmann–L?ffler Manifold
Del Castillo, Estefanía,Martínez, Mario D.,Bosnidou, Alexandra E.,Duhamel, Thomas,O'Broin, Calvin Q.,Zhang, Hongwei,Escudero-Adán, Eduardo C.,Martínez-Belmonte, Marta,Mu?iz, Kilian
supporting information, p. 17225 - 17229 (2018/11/10)
An innovative approach to position-selective polyhalogenation of aliphatic hydrocarbon bonds is presented. The reaction proceeded within the Hofmann-L?ffler manifold with amidyl radicals as the sole mediators to induce selective 1,5- and 1,6-hydrogen-atom transfer followed by halogenation. Multiple halogenation events of up to four innate C?H bond functionalizations were accomplished. The broad applicability of this new entry into polyhalogenation and the resulting synthetic possibilities were demonstrated for a total of 27 different examples including mixed halogenations.
PRODUCTION METHOD OF DIISOBUTYL CARBINOL BY HYDROGENATION OF DIISOBUTYL KETONE
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Paragraph 0022, (2016/12/22)
PROBLEM TO BE SOLVED: To provide a production method for producing efficiently diisobutyl carbinol having a small content of a ketone body, which is suitable for producing hydrogen peroxide by an anthraquinone method by hydrogenation of diisobutyl ketone. SOLUTION: A production method of diisobutyl carbinol has following steps 1 and 2. Step 1: diisobutyl ketone is hydrogenated at a temperature of 130°C-200°C and at a pressure of 0.1 MPa or higher in the presence of a catalyst containing one or more kinds of metal atoms selected from among copper, zinc, chromium, palladium, rhodium, ruthenium and platinum. Step 2: after finish of step 1, the temperature is lowered to 120°C or lower, while keeping the pressure at 0.1 MPa or higher. COPYRIGHT: (C)2015,JPO&INPIT
