108153-42-0

Basic information

• Product Name: 2-Hydroxy-4-methanesulfonylbenzoicacid
• Synonyms: 2-Hydroxy-4-methanesulfonylbenzoicacid
• CAS NO: 108153-42-0
• Molecular Weight: 216.215
• Mol File: 108153-42-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Hydroxy-4-methanesulfonylbenzoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-4-methanesulfonylbenzoicacid(108153-42-0)
• EPA Substance Registry System: 2-Hydroxy-4-methanesulfonylbenzoicacid(108153-42-0)

Safety Data

• Hazardous Substances Data: 108153-42-0(Hazardous Substances Data)

Upstream product

• 114086-41-8 4-methanesulfonyl-2-methoxybenzoic acid 
• 93276-65-4 2'-methoxy-4'-methylthioacetophenone 
• 51788-80-8 1-(4-fluoro-2-methoxy-phenyl)-ethanone 
• 1481-27-2 4-Fluoro-2-hydroxyacetophenone 
• 104206-82-8 mesotrione 
• 94231-96-6 2,2'-dihydroxy-4,4'-disulfanediyl-di-benzoic acid 
• 87703-95-5 4-thiosalicylic acid 
• 67127-67-7 2-hydroxy-4-(methylthio)benzoic acid 

Relevant articles and documents

The photo-degradation of mesotrione, a triketone herbicide, in the presence of CuII ions

The study focuses first on the complexation of CuII ions with mesotrione. Experimental absorption spectra combined with quantum chemical calculations highlight that CuII ions bind to the molecule in bidentate mode between O1 and O7 atoms. The calculated electronic transitions of the complex show that three of them are mostly ligand-to-ligand electron transfer while the lowest-energy one involves a ligand-to-metal charge transfer (LMCT). The second aim of this work is to explore the effect of CuII complexation on the photo-degradation of mesotrione. The kinetics and mechanisms of the reactions are proposed on the basis of the experimental results. The effect of different parameters such as the irradiation wavelength, the oxygen concentration and the pH of the mixture and also the production of reactive species such as hydroxyl radicals is investigated. The photochemical degradation of mesotrione in water arises from the triplet excited state of the molecule and results in a photo-hydrolysis process. For the complex, by exciting mainly in its LMCT absorption band, an electron transfer between copper and mesotrione probably occurs and the mechanism of mesotrione-CuII photo-degradation differs: in addition to the photo-hydrolysis route, a photo-cyclisation process takes place and the oxidation of the ligand is accompanied by the reduction of CuII ions.

MODULATORS OF DOPAMINE NEUROTRANSMISSION

The present invention relates to novel1-(4H-1,3-benzodioxin-2-yl)methanamine derivatives, useful as modulators of dopamine neurotransmission, and more specifically asdopaminergic stabilizers. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.