108166-23-0

Basic information

• Product Name: N-([1,1'-biphenyl]-4-yl)-2-methylbenzamide
• Synonyms: N-([1,1'-biphenyl]-4-yl)-2-methylbenzamide
• CAS NO: 108166-23-0
• Molecular Weight: 287.361
• Mol File: 108166-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-([1,1'-biphenyl]-4-yl)-2-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-([1,1'-biphenyl]-4-yl)-2-methylbenzamide(108166-23-0)
• EPA Substance Registry System: N-([1,1'-biphenyl]-4-yl)-2-methylbenzamide(108166-23-0)

Safety Data

• Hazardous Substances Data: 108166-23-0(Hazardous Substances Data)

Upstream product

• 92-67-1 4-phenylalanine 
• 933-88-0 ortho-toluoyl chloride 
• 95-49-8 2-methylchlorobenzene 

Downstream Products

• 36752-78-0 2-([1,1’-biphenyl]-4-yl)isoindolin-1-one 

Relevant articles and documents

Transition metal free intramolecular selective oxidative C(sp3)-N coupling: Synthesis of N-aryl-isoindolinones from 2-alkylbenzamides

A synthetic method has been developed for the preparation of biologically important isoindolinones including indoprofen and DWP205190 drugs from 2-alkylbenzamide substrates by transition metal-free intramolecular selective oxidative coupling of C(sp3)-H and N-H bonds utilizing iodine, potassium carbonate and di-tert-butyl peroxide in acetonitrile at 110-140 °C.