108238-41-1 Usage
Description
3,6-Dihydroxyflavone is a naturally occurring flavonoid compound characterized by the presence of two hydroxyl groups at the 3rd and 6th positions of the flavone nucleus. It is known for its diverse biological activities and potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
3,6-Dihydroxyflavone is used as a pharmaceutical intermediate for the development of drugs targeting various health conditions. Its ability to induce oxidative stress and apoptosis makes it a promising candidate for the treatment of cancer and other diseases characterized by uncontrolled cell proliferation.
Used in Cell Survival Applications:
In the field of cell biology and research, 3,6-dihydroxyflavone is utilized as a tool to study cell survival mechanisms. By inducing oxidative stress and apoptosis, it helps researchers understand the complex processes involved in cell death and survival, which can be crucial for developing targeted therapies and understanding the underlying mechanisms of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 108238-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,2,3 and 8 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 108238-41:
(8*1)+(7*0)+(6*8)+(5*2)+(4*3)+(3*8)+(2*4)+(1*1)=111
111 % 10 = 1
So 108238-41-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H10O4/c16-10-6-7-12-11(8-10)13(17)14(18)15(19-12)9-4-2-1-3-5-9/h1-8,16,18H
108238-41-1Relevant articles and documents
Pharmacophore model of the quercetin binding site of the SIRT6 protein
Ravichandran,Singh,Donnelly,Migliore,Johnson,Fishwick,Luke,Martin,Maudsley,Fugmann,Moaddel
, p. 38 - 46 (2014/03/21)
SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. We have previously reported on the identification of quercetin and vitexin as SIRT6 inhibitors,
