1082512-40-0Relevant articles and documents
Method for synthesizing homoallylamine compounds
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Paragraph 0024-0027; 0032-0035, (2020/05/01)
The invention discloses a method for synthesizing homoallylamine compounds, and belongs to the field of organic synthesis. N,N-acetal compounds represented by formula (I) are used as a substrate, andreact with a nucleophilic reagent allyl silicon compound represented by formula (II) under the activation of a Lewis acid to efficiently prepare the homoallylamine compounds represented by formula (III), and the yield can reach 85%. The method is simple and green, can efficiently obtain the target product, and has very good industrial application prospects.
Zinc-mediated allylation and alkylation of aminals in the presence of TMSCl and diisopropylamine
Hatano, Bunpei,Nagahashi, Keita,Kijima, Tatsuro
supporting information; scheme or table, p. 9188 - 9191 (2009/04/11)
(Chemical Equation Presented) An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.