108274-33-5 Usage
Description
5-(bromomethyl)-2-(trifluoromethyl)pyridine is an organic compound characterized by its pyridine ring structure, which features a bromomethyl group at the 5th position and a trifluoromethyl group at the 2nd position. 5-(bromomethyl)-2-(trifluoromethyl)pyridine is known for its reactivity and structural diversity, making it a valuable intermediate in the synthesis of various pharmaceuticals and chemical products.
Uses
Used in Pharmaceutical Industry:
5-(bromomethyl)-2-(trifluoromethyl)pyridine is used as a synthetic intermediate for the preparation of aryl piperidines and piperazines. These compounds serve as inducers of LDL-receptor expression, which can be beneficial in the treatment of conditions related to lipid metabolism and cardiovascular health.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-(bromomethyl)-2-(trifluoromethyl)pyridine is utilized as a building block for the creation of more complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its unique structural features allow for a wide range of reactions and modifications, making it a versatile component in the development of new compounds with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 108274-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,2,7 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 108274-33:
(8*1)+(7*0)+(6*8)+(5*2)+(4*7)+(3*4)+(2*3)+(1*3)=115
115 % 10 = 5
So 108274-33-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrF3N/c8-3-5-1-2-6(12-4-5)7(9,10)11/h1-2,4H,3H2
108274-33-5Relevant articles and documents
Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia
Liu, Ping,Wang, Liping,Dubois, Byron G.,Colandrea, Vincent J.,Liu, Rongqiang,Cai, Jiaqiang,Du, Xiaoxing,Quan, Weiguo,Morris, William,Bai, Jianwu,Bishwokarma, Bimjhana,Cheng, Mangeng,Piesvaux, Jennifer,Ray, Kallol,Alpert, Carla,Chiu, Chi-Sung,Zielstorff, Mark,Metzger, Joseph M.,Yang, Liming,Leung, Dennis,Alleyne, Candice,Vincent, Stella H.,Pucci, Vincenzo,Li, Xiaofang,Crespo, Alejandro,Stickens, Dominique,Hale, Jeffrey J.,Ujjainwalla, Feroze,Sinz, Christopher J.
, p. 1193 - 1198 (2018/12/11)
We report herein the design and synthesis of a series of orally active, liver-targeted hypoxia-inducible factor prolyl hydroxylase (HIF-PHD) inhibitors for the treatment of anemia. In order to mitigate the concerns for potential systemic side effects, we
Nitromethylene derivatives and their use as insecticides
-
, (2008/06/13)
The present invention provides novel nitromethylene derivatives of the formula (I) STR1 wherein R represents a hydrogen atom or an alkyl group, X represents a haloalkyl, haloalkoxy, haloalkylthio, haloalkylsulfinyl, haloalkylsulfonyl, nitro, cyano, thiocyanato, haloalkenyl, haloalkynyl, hydroxyl, alkoxycarbonyl, amino, acyl, dialkylamino, acylamino or alkoxy group, l represents 1, 2 or 3 provided that when l is 1, X does not represent an alkoxy group and when l is 2 or 3, not all substituents X represent an alkoxy group, m represents 2, 3 or 4, and n represents 0 or 1, and the use of the new compounds as insecticides.
