1083158-65-9

Basic information

• Product Name: N-[2-Amino-6-methyl-4-(1-methyl-1H-benzimidazol-2-yl)phenyl]butanamide
• CAS NO: 1083158-65-9
• Molecular Formula: C19H22N4O
• Molecular Weight: 322.41
• Mol File: 1083158-65-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[2-Amino-6-methyl-4-(1-methyl-1H-benzimidazol-2-yl)phenyl]butanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-Amino-6-methyl-4-(1-methyl-1H-benzimidazol-2-yl)phenyl]butanamide(1083158-65-9)
• EPA Substance Registry System: N-[2-Amino-6-methyl-4-(1-methyl-1H-benzimidazol-2-yl)phenyl]butanamide(1083158-65-9)

Safety Data

• Hazardous Substances Data: 1083158-65-9(Hazardous Substances Data)

Upstream product

• 1083158-66-0 N-[2-methyl-4-(1-methylbenzimidazole)-2-yl-6-nitrophenyl]-butanamide 

Downstream Products

• 1098100-85-6 N-((2-cyano-biphenyl-4'-methyl)amino-6-methyl-4-(1-methyl-1H-benzo[d]imidazol-2-yl)phenyl)butyramide 
• 1248624-37-4 C₃₇H₃₉N₅O₂ 

Relevant articles and documents

Concise synthesis of telmisartan via decarboxylative cross-coupling

(Chemical Equation Presented) An efficient synthesis of the angiotensin II receptor antagonist telmisartan is presented involving a decarboxylative cross-coupling of isopropyl phthalate (1) with 2-(4-chlorophenyl)-1,3-dioxolane (2c) as the key step (85% yield). The benzimidazole moiety is constructed regioselectively via a reductive animation-condensation sequence, replacing the previously published route via alkylation of the preformed benzimidazole. The product is obtained in an overall yield of 35% in a convergent synthesis with the longest sequence consisting of eight steps.