108378-40-1

Basic information

• Product Name: 4-oxo-3-phenylthiopentanenitrile
• Synonyms: 4-oxo-3-phenylthiopentanenitrile
• CAS NO: 108378-40-1
• Molecular Weight: 205.28
• Mol File: 108378-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-oxo-3-phenylthiopentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-3-phenylthiopentanenitrile(108378-40-1)
• EPA Substance Registry System: 4-oxo-3-phenylthiopentanenitrile(108378-40-1)

Safety Data

• Hazardous Substances Data: 108378-40-1(Hazardous Substances Data)

Upstream product

• 624-75-9 iodoacetonitrile 
• 5042-53-5 1-(phenylsulfanyl)acetone 

Downstream Products

• 108378-42-3 4-hydroxy-3-phenylthiopentanenitrile 

Relevant articles and documents

Rearrangements of 2-Phenylthioethanols with Alkenyl, Alkynyl, Ester, and Other Functionalised Alkyl Substituents at the Migration Origin: Synthesis of γ-Phenylthiocrotonate Esters

The effects of functional groups near the migration origin in and PhS shifts are explored: an α-CO2R group prevents migration, α or β vinyl groups have only steric effects, alkynyl or CO2Et groups encourage rearrangement and provide routes to γ-phenylthio unsaturated esters and ketones.