108447-01-4

Basic information

• Product Name: 4-bromo-5-methoxy-1,2-phenylenediamine
• Synonyms: 4-bromo-5-methoxy-1,2-phenylenediamine
• CAS NO: 108447-01-4
• Molecular Weight: 217.065
• Mol File: 108447-01-4.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 4-bromo-5-methoxy-1,2-phenylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-5-methoxy-1,2-phenylenediamine(108447-01-4)
• EPA Substance Registry System: 4-bromo-5-methoxy-1,2-phenylenediamine(108447-01-4)

Safety Data

• Hazardous Substances Data: 108447-01-4(Hazardous Substances Data)

Usage

General Description

4-bromo-5-methoxy-1,2-phenylenediamine, also known as 4-Bromo-5-methoxy-o-phenylenediamine, is a chemical compound with the molecular formula C6H8BrNO. It is a derivative of phenylenediamine and is commonly used in the production of hair dyes and other cosmetic products. The compound is a dark brown to black solid, and its chemical properties make it suitable for use in oxidative hair dye formulations. It acts as a colorant by forming colored complexes with oxidation products on the hair, and it is also used for its antibacterial properties. However, it is important to handle and use this compound with caution, as it can cause skin and eye irritation and may be harmful if ingested or inhaled.

Upstream product

• 6943-69-7 5-bromo-4-methoxy-2-nitro-phenylamine 
• 19056-41-8 3-bromo-p-anisidine 
• 16133-49-6 5-methoxy-2-nitroaniline 
• 173312-36-2 4-bromo-5-methoxy-2-nitrobenzeneamine 
• 51-66-1 4-methoxyacetanilide 
• 7357-66-6 N-(5-bromo-4-methoxy-2-nitrophenyl)acetamide 
• 6943-73-3 N-(3-bromo-4-methoxyphenyl)acetamide 
• 93702-76-2 8-methoxy-7-bromo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepinone-2 

Downstream Products

• 1008361-65-6 5-bromo-6-methoxy-1H-benzo[d]imidazole 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR MODULATING SPLICING

Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

Heterocyclic compound used as MNK inhibitor

The invention relates to a heterocyclic compound, a pharmaceutical composition containing the heterocyclic compound, a preparation method thereof, and application thereof used as a mitogen activated protein kinase interacting kinase 1 and 2-MNK1/MNK2 inhibitor. The inhibitor is the heterocyclic compound as shown in the formula (I), or its pharmaceutically acceptable salt, prodrug, solvent compound, polycrystal, isomer, stable isotope derivative or a pharmaceutical composition containing the heterocyclic compound. The compound of the invention can be used for treating or preventing MNK-mediatedrelated diseases, such as cancers.

HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES

Provided herein are heterocyclic compounds for treatment of CSF1R, FLT3, KIT, and/or PDGFRβ kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.