108478-16-6

Basic information

• Product Name: 3-Hydroxy-1,2-diphenyl-1-propanone
• Synonyms: 3-Hydroxy-1,2-diphenyl-1-propanone
• CAS NO: 108478-16-6
• Molecular Weight: 226.275
• Mol File: 108478-16-6.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 3-Hydroxy-1,2-diphenyl-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-1,2-diphenyl-1-propanone(108478-16-6)
• EPA Substance Registry System: 3-Hydroxy-1,2-diphenyl-1-propanone(108478-16-6)

Safety Data

• Hazardous Substances Data: 108478-16-6(Hazardous Substances Data)

Upstream product

• 451-40-1 phenyl benzyl ketone 
• 50-00-0 formaldehyd 
• 3923-51-1 1,1-diphenylprop-2-en-1-ol 
• 100-42-5 styrene 
• 98-88-4 benzoyl chloride 
• 591-50-4 iodobenzene 
• 5773-56-8 1,2-Diphenylethanol 
• 5669-11-4 3-oxo-2,3-diphenylpropanal 
• 5411-12-1 chalcone epoxide 
• 94-41-7 benzalacetophenone 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 66003-76-7 Diphenyliodonium triflate 
• 96-09-3 styrene oxide 

Downstream Products

• 4452-11-3 1,2-diphenylprop-2-en-1-one 
• 84980-02-9 1,2-diphenyl-1,3-propanediol 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 
• 93-58-3 benzoic acid methyl ester 
• 16619-12-8 2-phenyl-indan-1-one 
• 14367-02-3 erythro-1,2-diphenyl-1,3-propanediol 

Relevant articles and documents

Three-Component Ni-Catalyzed Silylacylation of Alkenes

A Ni-catalyzed silylacylation of alkenes is presented. The reaction combines alkenes, ClZnSiR3, and acid chlorides to provide rapid access to β-silyl ketones. Importantly, the method involves a [Ni]-SiR3 complex as a catalytic intermediate, which is rarely described for three-component alkene functionalization. Finally, the synthetic utility of the products is demonstrated, and the mechanistic details are described.

Organoiodine-induced hydroxylation as well as enantioselective alkoxylation/hydroxylation of allylic alcohols via 1,2- aryl migration

A new method for the hydroxylation of allylic alcohols using [hydroxyl(tosyloxy)iodo]benzene (HTIB) as both oxidant and reagent has been developed. Meanwhile, the enantioselective alkyoxylation as well as hydroxylation catalyzed by simple chiral iodine be

Visible-light-induced oxidative lignin c-c bond cleavage to aldehydes using vanadium catalysts

Lignin is the largest carrier of aromatics on earth, and its depolymerization can afford value-Added aromatic products. Direct cleavage of the C-C bonds in lignin linkages is significant, but it is challenging to obtain low-molecular-weight aromatic monomers. Herein, using vanadium catalysts under visible light, we selectively cleave the C-C bonds in β-1 and β-O-4 interlinkages occluded in lignin models and extracts by an oxidative protocol. Visible light irradiation triggered single electron transfer between the substrate and the catalyst, which further induced the selective Cα-Cβ bond cleavage and generated the final aromatic products through radical intermediates. Using this photocatalytic chemistry, the reactivity of lignin models and the selectivity of Cα-Cβ bond cleavage were significantly improved. More importantly, this protocol affords aromatic monomers through the fragmentation of organosolv lignins even at room temperature, indicating the potential of photocatalytic C-C bond cleavage of lignin linkages under ambient conditions.