108541-48-6

Basic information

• Product Name: 3-Cyclohexene-1-Methanol Methanesulfonate
• Synonyms: 3-Cyclohexene-1-Methanol Methanesulfonate
• CAS NO: 108541-48-6
• Molecular Formula: C₈H₁₄O₃S
• Molecular Weight: 190.25996
• Product Categories: Intermediates, Miscellaneous Reagents
• Mol File: 108541-48-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Dichloromethane, Diethyl Ether, Ethyl Acetate
• CAS DataBase Reference: 3-Cyclohexene-1-Methanol Methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexene-1-Methanol Methanesulfonate(108541-48-6)
• EPA Substance Registry System: 3-Cyclohexene-1-Methanol Methanesulfonate(108541-48-6)

Safety Data

• Hazardous Substances Data: 108541-48-6(Hazardous Substances Data)

Usage

Description

3-Cyclohexene-1-Methanol Methanesulfonate is a cyclohexene derivative that is found in the essential oil of various citrus varieties. It is a colorless oil with unique chemical properties that make it a valuable reactant in the synthesis of certain compounds.

Uses

Used in Pharmaceutical Industry:
3-Cyclohexene-1-Methanol Methanesulfonate is used as a reactant in the preparation of Cinitapride (C441990), a medication used to treat gastrointestinal disorders. Its unique chemical structure allows for the synthesis of this important drug, contributing to the development of effective treatments for various conditions.
Used in Flavor and Fragrance Industry:
As a component of essential oils found in citrus varieties, 3-Cyclohexene-1-Methanol Methanesulfonate is used as a flavoring agent and fragrance ingredient. Its distinct aroma and taste properties make it a valuable addition to the creation of various food and cosmetic products, enhancing their sensory appeal.
Used in Chemical Synthesis:
3-Cyclohexene-1-Methanol Methanesulfonate is also used as a protected 3-Cyclohexene-1-methanol (C988020) in chemical synthesis processes. Its ability to be selectively deprotected and converted into other useful compounds makes it a versatile building block in the synthesis of a wide range of chemical products.

Upstream product

• 100-50-5 3-Cyclohexene-1-carboxaldehyde 
• 103668-33-3 3-hydroxymethylcyclohexene 
• 124-63-0 methanesulfonyl chloride 
• 72581-32-9 cyclohex-3-enylmethanol 

Downstream Products

• 10468-33-4 2-(cyclohex-3-en-1-yl)acetamide 
• 40496-47-7 N-[2-(cyclohex-3-en-1-yl)ethyl]benzamide 
• 34956-61-1 2-(cyclohex-3-en-1-yl)acetonitrile 
• 40496-65-9 1-amino-2-(3-cyclohexen-1-yl) ethane 
• 103946-55-0 bis(3,4-epoxycyclohexylmethyl) ether 
• 142991-91-1 acetoxyacetic acid 
• 158213-00-4 (hydroxy)acetic acid 
• 32591-23-4 methyl N-<(3-cyclohexen-1-yl)methyl>carbamate 
• 128892-12-6 (phenylthio)acetic acid methyl ester 
• 128911-32-0 N-(2-(1-cyclohexen-1-yl)ethyl)-N-(methoxycarbonyl)glycine methyl ester 

Relevant articles and documents

Intramolecular Pyridinium Oxide Cycloadditions: Systematic Study of Substitution, Diastereoselectivity, and Regioselectivity

Intramolecular pyridinium oxide cycloadditions form complex polycyclic nitrogenous architectures. The diastereoselectivity and regioselectivity of pyridinium oxide cycloadditions was systematically investigated for the first time using complex substrates.

CURABLE EPOXY RESIN COMPOSITION AND CURED PRODUCT THEREOF, DIOLEFIN COMPOUND AND PRODUCTION METHOD THEREFOR, AND PRODUCTION METHOD FOR DIEPOXY COMPOUND

An object of the present invention is to provide a curable epoxy resin composition, which is cured to provide a cured product having a high glass-transition temperature and particularly having excellent balance between heat resistance and transparency. The present invention relates to a curable epoxy resin composition comprising an alicyclic epoxy compound (A) represented by the following formula (1) and a curing agent (B), or a curable epoxy resin composition comprising an alicyclic epoxy compound (A) represented by the following formula (1) and a curing catalyst (C). [Formula 1] wherein R 1 to R 22 , which may be the same or different, each represent a hydrogen atom, a methyl group or an ethyl group; and m and n, which may be the same or different, each represent an integer of 1 to 4.

Cycloalkylmethyl Radicals. Part 4. Electron Spin Resonance Study of Conformational Equilibria in Cyclohexenylmethyl and 4-Alkylcyclohexenylmethyl Radicals

For cyclohex-2-enylmethyl and 4-alkoxycyclohex-2-enylmethyl radicals the quasi-axial and the quasi-equatorial conformers can both be observed by e.s.r. spectroscopy.Similary, the axial and equatorial conformers of cyclohex-3-enylmethyl radical can be distinguished by e.s.r. spectroscopy.The conformational free-energy difference of the CH2. group in the 2-position, -ΔGdeg300, was found to be 0.17 +/- 0.03 kcal mol-1 and in the 3-position -ΔGdeg300=0.0 +/- 0.1 kcal mol-1.The Arrhenius parameters for inversion of the half-chair conformation of cyclohex-2-enylmethyl radical were determined by lineshape analysis of the exchange-broadened spectra and found to be: log(kf/s-1)=12.3 - (5.7 kcal mol-1)/2.3RT and log(kb/s-1)=12.0 - (5.5 kcal mol-1)/2.3RT.The barrier to rotation about the C.α-Cβ bond in a cyclohexenylmethyl radicals is much less than the barrier in a cyclohexylmethyl radical because the former radical has only one syn-axial hydrogen on C(5) to impede the rotation whereas the latter radical has two syn-axial hydrogens on C(3) and C(5).