1088706-45-9

Basic information

• Product Name: C₂₆H₃₃NO₂
• Synonyms: C₂₆H₃₃NO₂
• CAS NO: 1088706-45-9
• Molecular Weight: 391.554
• Mol File: 1088706-45-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₃NO₂(1088706-45-9)
• EPA Substance Registry System: C₂₆H₃₃NO₂(1088706-45-9)

Safety Data

• Hazardous Substances Data: 1088706-45-9(Hazardous Substances Data)

Upstream product

• 16096-33-6 1-phenyl-1H-indole 
• 26728-44-9 ethyl rac-3,7-dimethyloct-6-enoate 

Relevant articles and documents

Gold(I)-catalyzed intermolecular hydroarylation of alkenes with indoles under thermal and microwave-assisted conditions

An efficient method for intermolecular hydroarylation of aryl and aliphatic alkenes with indoles using a combination of [(PR3)AuCl]/AgOTf as catalyst under thermal and microwave-assisted conditions has been developed. The gold(I)-catalyzed reactions of indoles with aryl alkenes were achieved in toluene at 85°C over a reaction time of 1-3 h with 2 mol% of [(PR 3)AuCl]/ AgOTf as catalyst. This method works for a variety of styrenes bearing electron-deficient, electron-rich, and sterically bulky substituents to give the corresponding products in good to high yields (60-95%). Under microwave irradiation, coupling of unactivated aliphatic alkenes with indoles gave the corresponding adducts in up to 90% yield. Selective hydroarylation of terminal C=C bond of conjugated dienes with indoles gave good product yields (62-81 %). On the basis of deuteriumlabeling experiments, a reaction mechanism involving nucleophilic attack of Au(I)-coordinated alkenes by indoles is proposed.