1089216-05-6Relevant articles and documents
Hydrogen-bonded deugdan heterocomplex: Structure and stability and a scalable synthesis of DeUG with reactive functionality
Kuykendall, Darrell W.,Anderson, Cyrus A.,Zimmerman, Steven C.
supporting information; experimental part, p. 61 - 64 (2009/07/04)
A convenient, scalable synthesis of the supramolecular building block 7-deazaguanine-based urea (DeUG) is reported. Incorporation of reactive moieties (DeUG azide 10 and alkyne 11 for copper-catalyzed azide-alkyne cycloadditions, "click chemistry") and a demonstration of transesterification (DeUG glycol, 12) highlights the versatility. X-ray structures of DeUG and a DeUG-DAN heterocomplex were obtained. Kassoc for the 1.2 heterocomplex was estimated to be 2 x 108 M-1 in chloroform.