108975-02-6

Basic information

• Product Name: 3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one
• Synonyms: 3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one
• CAS NO: 108975-02-6
• Molecular Weight: 232.323
• Mol File: 108975-02-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one(108975-02-6)
• EPA Substance Registry System: 3-cyclohexyl-1-(2-hydroxyphenyl)propan-1-one(108975-02-6)

Safety Data

• Hazardous Substances Data: 108975-02-6(Hazardous Substances Data)

Upstream product

• 1647-26-3 1-bromo-2-cyclohexylethane 
• 118-55-8 phenyl Salicylate 
• 108-95-2 phenol 
• 39098-75-4 3-cyclohexylpropionyl chloride 
• 94157-86-5 3-Cyclohexylpropionsaeure-phenylester 

Relevant articles and documents

Nickel-Catalyzed Directed Cross-Electrophile Coupling of Phenolic Esters with Alkyl Bromides

Herein, we demonstrate the successful use of robust phenolic esters as an electrophilic acyl source in the reaction with diverse primary and secondary unactivated alkyl bromides. The cleavage of the relatively inert C-O bond is facilitated by the neighboring coordinating hydroxyl or sulfonamide moiety. By circumventing the use of pregenerated organometallics, this method allows efficient preparation of a variety of o-hydroxyl and tosyl-protected o-amino aryl ketones with high compatibility with a wide range of functionalities.