1092306-36-9Relevant articles and documents
Visible Light Promoted Chan-Lam Reaction and Cycloaddition to Prepare Chromeno[4,3-c]isoxazolidines in One-Pot Reaction
Huang, Bing-Qing,Ma, Xiao-Pan,Mo, Dong-Liang,Zhao, Jie,Zhu, Bin-Can
supporting information, p. 4575 - 4581 (2021/08/13)
A variety of chromeno[4,3-c]isoxazolidines were prepared in good yields through visible light promoted Chan-Lam reaction and [3+2] cycloaddition cascade reaction in one pot. Mechanistic studies showed that visible light promoted both Chan-Lam reaction and cycloaddition. The obtained products were converted to various useful chromenone derivatives. Moreover, the reaction was easily performed at gram scales with the purification of products without column chromatography and used to efficiently synthesize estrone-derived chromeno[4,3-c]isoxazolidine. (Figure presented.).
Cerium(III)-catalyzed facile synthesis of dihydrobenzofuran-tethered pyridines and dihydroquinolin-5(6 H)-ones from -enaminones
Kantevari, Srinivas,Addla, Dinesh,Sridhar, Balasubramanian
experimental part, p. 3745 - 3754 (2011/01/03)
A series of novel dihydrobenzofuran-tethered pyridines, dihydroquinolin-5(6H)-ones, and indeno[1,2-b]pyridin-5-ones were synthesized in very good yields by CeCl37H2O-NaI catalyzed one-pot condensation of variants of the Bohlmann-Rahtz reaction, viz. -enaminones derived from 7-acetyldihydrobenzofurans, acyclic and cyclic 1,3-dicarbonyls, and ammonium acetate. The protocol offers the advantages of easily accessible substrates, shorter reaction times, and easy work-up with a readily available catalyst. Further more, dihydrobenzofuran-substituted 2-(chloromethyl)pyridine was derivatized to its synthetic hybrid by reacting with piperazine. Georg Thieme Verlag Stuttgart.
