1092578-27-2

Basic information

• Product Name: prednisone
• Synonyms: prednisone
• CAS NO: 1092578-27-2
• Molecular Weight: 523.54
• Mol File: 1092578-27-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: prednisone(CAS DataBase Reference)
• NIST Chemistry Reference: prednisone(1092578-27-2)
• EPA Substance Registry System: prednisone(1092578-27-2)

Safety Data

• Hazardous Substances Data: 1092578-27-2(Hazardous Substances Data)

Upstream product

• 53-03-2 Prednison 
• 7693-46-1 4-Nitrophenyl chloroformate 

Downstream Products

• 1092578-28-3 C₄₈H₆₀N₄O₁₉ 

Relevant articles and documents

Switch off/switch on regulation of drug cytotoxicity by conjugation to a cell targeting peptide

Bi-nuclear amino acid platforms loaded with various drugs for conjugation to a peptide carrier were synthesized using simple and convenient orthogonally protective solid-phase organic synthesis (SPOS). Each arm of the platform carries a different anticancer agent linked through the same or different functional group, providing discrete chemo-and bio-release profiles for each drug, and also enabling switch off/switch regulation of drug cytotoxicity by conjugation to the platform and to a cell targeting peptide. The versatility of this approach enables efficient production of drug-loaded platforms and determination of favorable drug combinations/modes of linkage for subsequent conjugation to a carrier moiety for targeted cancer cell therapy. The results presented here potentiate the application of amino acid platforms for targeted drug delivery (TDD).