109347-44-6Relevant articles and documents
Preparation method of 4-methylsulphonylphenylacetic acid
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, (2018/04/01)
The invention belongs to the field of organic synthesis and provides a preparation method of 4-methylsulphonylphenylacetic acid. According to the preparation method, 4-methylthio benzaldehyde is prepared from thioanisole as a starting material through a Vilsmeier reaction and subjected to a Darzen reaction; a product is subjected to hydrolysis and decarboxylation, and 4-methylthio phenylacetaldehyde is obtained; 4-methylsulphonylphenylacetic acid is prepared from 4-methylthio phenylacetaldehyde through oxidization.