109352-73-0Relevant articles and documents
Synthesis of 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4, 10(5H)-triones as NMDA glycine-site antagonists
Brown, Dean G.,Urbanek, Rebecca A.,Bare, Thomas M.,McLaren, Frances M.,Horchler, Carey L.,Murphy, Megan,Steelman, Gary B.,Empfield, James R.,Forst, Janet M.,Herzog, Keith J.,Xiao, Wenhua,Dyroff, Martin C.,Lee, Chi-Ming C.,Trivedi, Shephali,Neilson, Kathy L.,Keith, Richard A.
, p. 3553 - 3556 (2007/10/03)
Several members of the 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4, 10(5H)-triones (2) have been identified as being potent and selective NMDA glycine-site antagonists. Increasing size of the alkyl substituent on the alpha-c