109361-28-6

Basic information

• Product Name: (1R,2R)-(-)-α-(1-isopropylaminoethyl)benzyl alcohol
• Synonyms: (1R,2R)-(-)-α-(1-isopropylaminoethyl)benzyl alcohol
• CAS NO: 109361-28-6
• Molecular Weight: 193.289
• Mol File: 109361-28-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (1R,2R)-(-)-α-(1-isopropylaminoethyl)benzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-(-)-α-(1-isopropylaminoethyl)benzyl alcohol(109361-28-6)
• EPA Substance Registry System: (1R,2R)-(-)-α-(1-isopropylaminoethyl)benzyl alcohol(109361-28-6)

Safety Data

• Hazardous Substances Data: 109361-28-6(Hazardous Substances Data)

Upstream product

• 60980-85-0 2,2,4-trimethyl-5-phenyl-2,3,4,5-tetrahydroisoxazole 
• 10020-96-9 (R)-Mandelonitrile 
• 917-64-6 methyl magnesium iodide 
• 120443-82-5 (R)-2-phenyl-2-(trimethylsiloxy)acetonitrile 
• 75-31-0 isopropylamine 
• 53643-20-2 (1R,2R)-norephedrine hydrochloride 
• 67-64-1 acetone 
• 37577-07-4 Norpseudoephedrine 
• 75-30-9 2-iodo-propane 
• 14838-15-4 u-2-amino-1-phenylpropan-1-ol 
• 52741-17-0 2-isopropylamino-1-phenyl-propan-1-one; hydrochloride 
• 16251-45-9 4,5-trans-4-Methyl-5-phenyl-1,3-oxazolidin-2-one 
• 54680-46-5 norephedrine 
• 4541-87-1 cis-1-phenylpropene oxide 

Downstream Products

• 24271-96-3 (1RS,2SR)-2-isopropylamino-1-(4-nitro-phenyl)-propan-1-ol 
• 112475-70-4 [((1R,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-isopropyl-amino]-acetic acid 
• 112475-70-4 [((1R,2S)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-isopropyl-amino]-acetic acid 
• 109242-48-0 (R)-3-[(E)-3-((2S,4R,5R)-3-Isopropyl-4-methyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-allyl]-cycloheptanone 
• 109361-27-5 (S)-3-[(E)-3-((2R,4R,5R)-3-Isopropyl-4-methyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-allyl]-cycloheptanone 
• 109242-49-1 (R)-3-[(E)-3-((2S,4R,5R)-3-Isopropyl-4-methyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-allyl]-cyclohexanone 
• 109242-47-9 (R)-3-[(E)-3-((2S,4R,5R)-3-Isopropyl-4-methyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-allyl]-cyclopentanone 
• 109361-26-4 (S)-3-[(E)-3-((2R,4R,5R)-3-Isopropyl-4-methyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-allyl]-cyclopentanone 
• 144032-34-8 N-((1R,2S)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-N-isopropyl-acetamide 
• 144032-34-8 N-((1R,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-N-isopropyl-acetamide 
• 109361-23-1 (2S,4R,5R)-2-Allyl-3-isopropyl-4-methyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide 

Relevant articles and documents

Vinylborane Formation in Rhodium-catalysed Hydroborations; Ligand-free Homogeneous Catalysis

The reaction of vinylarenes with oxazaborolidine 4 catalysed by (bis-alkene) rhodium chloride complexes leads exclusively to coproduction of (E)-vinylborane and ethylarene.

Stereoselective reactions, 25. Enantioselective deprotonation of prochiral 4-substituted cyclohexanones by chiral chelated lithium amides

Enantioselective deprotonation of prochiral 4-substituted cyclohexanones (4a-d) by chiral chelated lithium amides (8a-k) in the presence of excess trimethylsilyl chloride was realized to give the corresponding chiral silyl enol ethers (6a-d) in up to 89% ee. It is shown that enantioselectivity of the reaction is dependent on the solvent used, but becomes almost independent on the solvent in the presence of HMPA. The sense of asymmetric induction can be correlated to the configuration at the chiral carbon bearing amide nitrogen of the lithium amide.

Remarkable Enantioselective 1,4-Addition Reactions of Chiral Allylphosphonyl Anions (Ambident Nucleophiles) with Cyclic Enones (Ambident Electrophiles)

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