1093733-23-3

Basic information

• Product Name: N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-propanamide
• Synonyms: N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-propanamide
• CAS NO: 1093733-23-3
• Molecular Weight: 435.541
• Mol File: 1093733-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-propanamide(1093733-23-3)
• EPA Substance Registry System: N-[(1S,2R,3E)-2-hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]-propanamide(1093733-23-3)

Safety Data

• Hazardous Substances Data: 1093733-23-3(Hazardous Substances Data)

Upstream product

• 30364-55-7 succinimidyl propionate 
• 26993-30-6 Sphingosine-1-phosphate 

Relevant articles and documents

An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate

An efficient, one-pot procedure for the synthesis of ceramide 1-phosphates with varying N-acyl substituents, to serve as tool compounds for analytical and biological investigations, was developed. Sphingosine 1-phosphate was silylated in situ to increase its solubility and to protect the 3-hydroxy functionality and then allowed to react with activated acid derivatives in the presence of diisopropylethylamine. Simultaneous cleavage of the silyl protecting groups and separation from reagents and by-products was achieved by medium pressure chromatography on reversed phase material. Thus, ceramide 1-phosphates with various fatty acid chains and with fluorescent and affinity labels attached to the sphingoid backbone were prepared in good yields.