1093981-22-6

Basic information

• Product Name: 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole
• Synonyms: 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole
• CAS NO: 1093981-22-6
• Molecular Weight: 267.265
• Mol File: 1093981-22-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole(1093981-22-6)
• EPA Substance Registry System: 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole(1093981-22-6)

Safety Data

• Hazardous Substances Data: 1093981-22-6(Hazardous Substances Data)

Upstream product

• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 124443-67-0 1-[(4-fluorophenyl)methyl]-1H-benzimidazole 
• 51-17-2 benzoimidazole 

Downstream Products

• 1372608-95-1 1-(4-fluorobenzyl)-6-methoxy-1H-benzo[d]imidazol-2-amine 
• 83783-69-1 1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-amine 
• 1372608-86-0 2-amino-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-6yl formate 
• 1372608-92-8 6-chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-amine 
• 1372608-94-0 6-bromo-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-amine 
• 1372608-96-2 1-((4-fluorophenyl)(methoxy)methyl)-1H-benzo[d]imidazol-2-amine 
• 1372608-90-6 2-amino-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-6-yl methanesulfonate 
• 1372608-91-7 2-amino-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-6-yl trifluoromethanesulfonate 
• 1372608-87-1 2-amino-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-6yl acetate 
• 1372608-88-2 2-amino-1-(4-fluorobenzyl)-1H-benzo[d]imidazol-6-yl propionate 
• 1372608-89-3 2,2,2-trifluoro-N-(1-(4-fluorobenzyl)-6-hydroxy-1H-benzo[d]imidazol-2(3H)-ylidene)acetamide 
• 485835-59-4 (S)-tert-butyl (4-(methylthio)-1-oxo-1-(pyrrolidin-1-yl)butan-2-yl)carbamate 

Relevant articles and documents

Photochemical arylation of Bronsted acids with 2-azidobenzimidazole

Irradiation of N-benzylated 2-azidobenzimidazoles at 300 nm in the presence of an excess amount of carboxylic acids results in a novel regioselective synthesis of 2-amino-6-oxybenzimidazoles in isolated yields of 60-70 %. It is also possible to regioselectively introduce 6-bromo, 6-chloro, and 6-triflyloxy groups. Irradiation in dichloromethane in the absence of external nucleophiles revealed that after loss of nitrogen, the benzimidazolylnitrene probably undergoes coarctate ring opening to an N-cyano diaza-o-xylylene intermediate. Photolysis of 2-azidobenzimidazoles in the presence of carboxylic or sulfonic acidsleads to regioselective oxygenation of the 6-position in good yield. Copyright