109408-34-6

Basic information

• Product Name: N'-(N-benzoylglycinyl)isonicotinic hydrazide
• CAS NO: 109408-34-6
• Molecular Weight: 298.301
• Mol File: 109408-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-(N-benzoylglycinyl)isonicotinic hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(N-benzoylglycinyl)isonicotinic hydrazide(109408-34-6)
• EPA Substance Registry System: N'-(N-benzoylglycinyl)isonicotinic hydrazide(109408-34-6)

Safety Data

• Hazardous Substances Data: 109408-34-6(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 62912-04-3 1-(N-benzoyl-glycyloxy)-1H-benzotriazole 
• 39178-35-3 isonicotinoyl chloride hydrochloride 
• 2443-68-7 (2-hydrazinyl-2-oxoethyl)benzamide 
• 2979-64-8 hippuroylmercapto-acetic acid 

Relevant articles and documents

Microwave irradiation and diisopropylcarbodiimide (DIC)/7-aza-1- hydroxybenzotriazole (HOAt): A potent combination for synthesis of variuos hydrazide from N-protected amino acid and hydrazine

Here we describe a fast and rapid technique for preparation of amino acid hydrazide as well as peptide hydrazide derivatives using diisopropylcarbodiimide (DIC)/1-hydroxybenzotriazoles (HOXt) (X = A or B) under microwave irradiation employing a multimode reactor (Synthos 3000 Aton Paar, GmbH, 1400 W maximum magnetron). A comparison between conventional and microwave irradiation was described. The microwave methodology is rapid, convenient, proceeds under mild conditions. Diisopropylcarbodiimide (DIC)/7-aza-1-hydroxybenzotriazole (HOAt) always gave much better yield (95 - 98%) and purity than diisopropylcarbodiimide (DIC)/1-hydroxybenzotriazole (HOBt).