109432-97-5

Basic information

• Product Name: 1,1-Cyclohexanedicarboxylic acid, 3,4-bis(methylene)-, dimethyl ester
• CAS NO: 109432-97-5
• Molecular Formula: C12H16O4
• Molecular Weight: 224.257
• Mol File: 109432-97-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1-Cyclohexanedicarboxylic acid, 3,4-bis(methylene)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Cyclohexanedicarboxylic acid, 3,4-bis(methylene)-, dimethyl ester(109432-97-5)
• EPA Substance Registry System: 1,1-Cyclohexanedicarboxylic acid, 3,4-bis(methylene)-, dimethyl ester(109432-97-5)

Safety Data

• Hazardous Substances Data: 109432-97-5(Hazardous Substances Data)

Upstream product

• 115246-76-9 dimethyl 2-(2-propenyl)-2-(buta-2,3-dienyl)propane-1,3-dioate 
• 82167-48-4 2,3-bis<(trimethyksilyl)methyl>-1,3-butadiene 
• 3377-21-7 dimethyl 2-methylenemalonate 
• 82167-55-3 3,4-Bis-trimethylsilanylmethyl-cyclohex-3-ene-1,1-dicarboxylic acid dimethyl ester 
• 108561-17-7 dimethyl 2-(but-3-enyl)-2-(prop-2-ynyl)malonate 

Downstream Products

• 109432-98-6 5,5-bis(phenylsulfonyl)-1-octen-7-yne 

Relevant articles and documents

A rhodium catalyzed cycloisomerization and tandem Diels-Alder reaction for facile access to diverse bicyclic and tricyclic heterocycles

A regioselective distal cycloisomerization of 1,6-allenenes was successfully developed to afford six-membered ring exocyclic 1,3-dienes employing a rhodium/diphosphine catalyst system. Deuterium labelling experiments and DFT calculations were performed to provide insights into the reaction mechanism of this unprecedented transformation. In addition, one-pot tandem Diels-Alder reactions with various dienophiles could readily construct diverse bicyclic and tricyclic nitrogen heterocycles, which are ubiquitous core scaffolds for a variety of natural products and bioactives. High efficiency and exclusive chemo and regioselectivities for a broad substrate scope were achieved under mild conditions using a low catalyst loading of 0.5 mol%.

A NEW PALLADIUM CATALYST FOR INTRAMOLECULAR CARBAMETALATIONS OF ENYNES

The combination of (dba)3Pd2*CHCl3 plus a carboxylic acid effectively catalyzes cyclization of 1,6-enynes in which asymmetric induction may be achieved by use of enantiomerically pure carboxylic acids.

2,3-Bis-1,3-butadiene. A Conjunctive Reagent for Tandem Diels-Alder Reactions

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