109461-15-6 Usage
Description
Zolpidem 6-Carboxylic Acid is a major metabolite of Zolpidem, a medication used to treat insomnia. It is a yellow solid with chemical properties that make it a significant compound in the study of Zolpidem's metabolism and potential applications.
Uses
Used in Pharmaceutical Research:
Zolpidem 6-Carboxylic Acid is used as a research compound for understanding the metabolism of Zolpidem and its effects on the body. This knowledge can help in the development of improved treatments for insomnia and other sleep disorders.
Used in Drug Metabolism Studies:
As a major metabolite of Zolpidem, Zolpidem 6-Carboxylic Acid is used in drug metabolism studies to investigate the biotransformation processes and the role of metabolites in the therapeutic effects and side effects of the parent drug.
Used in Quality Control and Standardization:
Zolpidem 6-Carboxylic Acid is used as a reference compound in the quality control and standardization of pharmaceutical products containing Zolpidem. This ensures the consistency, purity, and potency of the medication being used for treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 109461-15-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,4,6 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 109461-15:
(8*1)+(7*0)+(6*9)+(5*4)+(4*6)+(3*1)+(2*1)+(1*5)=116
116 % 10 = 6
So 109461-15-6 is a valid CAS Registry Number.
109461-15-6Relevant articles and documents
Major metabolites of Zolpidem: Expeditious synthesis and mass spectra
Klupsch, Frederique,Houssin, Raymond,Humbert, Luc,Imbenotte, Michel,Henichart, Jean-Pierre,Lhermitte, Michel
, p. 1318 - 1321 (2008/09/21)
An expeditious route to the two major metabolites of Zolpidem - and readily applicable to the synthesis of the drug - was established via a cyclization reaction between a 2-aminopyridine and a suitable α-bromoacetophenone. The structures of the target compounds were confirmed from a 2D 1H- 15N NMR correlation. Their mass spectra contribute to a reliable toxicological identification of the drug in the case of drug-facilitated crimes.
