1094619-91-6

Basic information

• Product Name: 5-amino-3-(trichloromethyl)isothiazole-4-carbonitrile
• Synonyms: 5-amino-3-(trichloromethyl)isothiazole-4-carbonitrile
• CAS NO: 1094619-91-6
• Molecular Weight: 242.516
• Mol File: 1094619-91-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-amino-3-(trichloromethyl)isothiazole-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-3-(trichloromethyl)isothiazole-4-carbonitrile(1094619-91-6)
• EPA Substance Registry System: 5-amino-3-(trichloromethyl)isothiazole-4-carbonitrile(1094619-91-6)

Safety Data

• Hazardous Substances Data: 1094619-91-6(Hazardous Substances Data)

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 545-06-2 trichloroacetonitrile 

Downstream Products

• 1094619-94-9 6-(2-methoxyphenyl)-5-phenethyl-3-(trichloromethyl)isothiazolo[5,4-d]pyrimidin-4(5H)-one 
• 1094619-98-3 (R)-6-(2-methoxyphenyl)-4-oxo-5-(1-phenylpropan-2-yl)-isothiazolo[5,4-d]pyrimidine-3-carboxamide 
• 1094619-97-2 (R)-methyl 6-(2-methoxyphenyl)-4-oxo-5-(1-phenylpropan-2-yl)-isothiazolo[5,4-d]pyrimidine-3-carboxylate 
• 1094619-52-9 (R)-6-(2-hydroxyphenyl)-4-oxo-5-(1-phenylpropan-2-yl)-isothiazolo[5,4-d]pyrimidine-3-carbonitrile 
• 1094619-99-4 (R)-6-(2-methoxyphenyl)-4-oxo-5-(1-phenylpropan-2-yl)-isothiazolo[5,4-d]pyrimidine-3-carbonitrile 
• 1094619-93-8 6-(2-methoxyphenyl)-3-(trichloromethyl)isothiazolo[5,4-d]pyrimidin-4(5H)-one 

Relevant articles and documents

Synthesis of 4,5-disubstituted-3-trihalomethylisothiazoles

Herein, we describe the synthesis of 4,5-disubstituted-3-trihalomethylisothiazoles from trihaloacetonitriles and 2-cyanothioacetamides or 2-ethoxycarbonylthioacetamides. The reactivity of the necessary trihaloacetonitriles has a significant impact on the