Cas 1096156-23-8,ethyl 2-acetyl-4-methylthiazole-5-carboxylate

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Check Digit Verification of cas no

The CAS Registry Mumber 1096156-23-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,6,1,5 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1096156-23:
(9*1)+(8*0)+(7*9)+(6*6)+(5*1)+(4*5)+(3*6)+(2*2)+(1*3)=158
158 % 10 = 8
So 1096156-23-8 is a valid CAS Registry Number.

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1096156-23-8Relevant articles and documents

Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)

Farmer, Luc J.,Bemis, Guy,Britt, Shawn D.,Cochran, John,Connors, Martin,Harrington, Edmund M.,Hoock, Thomas,Markland, William,Nanthakumar, Suganthini,Taslimi, Paul,Haar, Ernst Ter,Wang, Jian,Zhaveri, Darshana,Salituro, Francesco G.

scheme or table, p. 6231 - 6235 (2009/08/07)

A series of SYK inhibitors based on the phenylamino pyrimidine thiazole lead 4 were prepared and evaluated for biological activity. Lead optimization provided compounds with nanomolar Ki's against SYK and potent inhibition in mast cell degranulation assays.

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1096156-23-8