1096545-12-8Relevant articles and documents
5-Membered cyclic hydroxamic acids as HDAC inhibitors
Mutule, Ilze,Borovika, Diana,Rozenberga, Elina,Romanchikova, Nadezhda,Zalubovskis, Raivis,Shestakova, Irina,Trapencieris, Peteris
, p. 216 - 223 (2015/04/14)
The new histone deacylases inhibitors (HDACi) were synthesized in the class of 5-membered cyclic hydroxamic acids (5-CHA), showing medium size CHA as a new Zn-binding group. New reaction sequence was proposed for the synthesis of 5-membered alkylidene-cyc