109768-67-4

Basic information

• Product Name: (4H-BENZO[D][1,3]THIAZIN-2-YL)-P-TOLYL-AMINE
• Synonyms: N-(4-methylphenyl)-4H-3,1-benzothiazin-2-amine
• CAS NO: 109768-67-4
• Molecular Formula: C₁₅H₁₄N₂S
• Molecular Weight: 254.35
• Mol File: 109768-67-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 422.5 °C at 760 mmHg
• Flash Point: 209.3 °C
• Appearance: /
• Density: 1.2 g/cm³
• Vapor Pressure: 2.4E-07mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: (4H-BENZO[D][1,3]THIAZIN-2-YL)-P-TOLYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4H-BENZO[D][1,3]THIAZIN-2-YL)-P-TOLYL-AMINE(109768-67-4)
• EPA Substance Registry System: (4H-BENZO[D][1,3]THIAZIN-2-YL)-P-TOLYL-AMINE(109768-67-4)

Safety Data

• Hazardous Substances Data: 109768-67-4(Hazardous Substances Data)

Usage

General Description

(4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine is a chemical compound with a molecular formula of C14H12N2S. It belongs to the class of benzo[d]thiazine compounds, which have various pharmacological activities. This specific compound has been studied for its potential use as a pharmaceutical drug due to its ability to act on certain biological targets and pathways. The compound has also been investigated for its potential role in the treatment of various diseases and conditions. Further research is needed to fully understand the properties and potential applications of (4H-Benzo[d][1,3]thiazin-2-yl)-p-tolyl-amine.

InChI:InChI=1/C15H14N2S/c1-11-6-8-13(9-7-11)16-15-17-14-5-3-2-4-12(14)10-18-15/h2-9H,10H2,1H3,(H,16,17)

Upstream product

• 106-49-0 p-toluidine 
• 5344-90-1 2-Aminobenzyl alcohol 
• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 109768-45-8 2-isothiocyanatobenzylpyridinium bromide 
• 108288-40-0 2-(bromomethyl)phenyl isothiocyanate 
• 109768-48-1 1-[2-(3-p-Tolyl-thioureido)-benzyl]-pyridinium; bromide 
• 109768-58-3 C₂₀H₁₉N₃S 

Relevant articles and documents

P(III)-Mediated Cascade C-N/C-S Bond Formation: A Protocol towards the Synthesis of N,S-Heterocycles and Spiro Compounds

A P(III)-mediated entry towards construction of C?N/C?S bond has been devised. The developed heterocyclization method was exercised for the synthesis of a diverse range of N,S-heterocycles and related spiro molecules. P(NMe2)3 revealed the maximum efficacies under the aerobic reaction conditions and a spectrum of bis-nucleophiles, and isothiocyanates were tolerated well to serve the access of manifold immense molecules. (Figure presented.).

2-ISOTHIOCYANATOBENZYLPYRIDINIUM BROMIDE - AN INTERMEDIATE FOR THE SYNTHESIS OF 2-ARYLAMINO-4H-BENZOTHIAZINES

2-Bromomethylphenyl isothiocyanate reacts with pyridine to yield 2-isothiocyanatobenzylpyridinium bromide, which afforded N-aryl-N'-(2-benzylpyridinium)thiourea bromides.Deprotonization of the latter with aqueous NaOH gave N-aryl-N'-(2-benzylpyridinium) t