1097722-44-5Relevant articles and documents
Design at the atomic level: Generation of novel hybrid biaryloxazolidinones as promising new antibiotics
Zhou, Jiacheng,Bhattacharjee, Ashoke,Chen, Shili,Chen, Yi,Duffy, Erin,Farmer, Jay,Goldberg, Joel,Hanselmann, Roger,Ippolito, Joseph A.,Lou, Rongliang,Orbin, Alia,Oyelere, Ayomi,Salvino, Joe,Springer, Dane,Tran, Jennifer,Wang, Deping,Wu, Yusheng,Johnson, Graham
scheme or table, p. 6179 - 6183 (2009/07/18)
From the X-ray crystal structures of linezolid and the non-selective antibiotic sparsomycin, we have derived a new family of hybrid oxazolidinones. From this initial compound set we have developed a new biaryloxazolidinone scaffold that shows both potent
