1098100-86-7

Basic information

• Product Name: 2-cyano-4'-[2-n-propyl-4-methyl-6-methylcarboxylate-benzimidazole-1-ylmethyl]biphenyl
• Synonyms: 2-cyano-4'-[2-n-propyl-4-methyl-6-methylcarboxylate-benzimidazole-1-ylmethyl]biphenyl
• CAS NO: 1098100-86-7
• Molecular Weight: 423.514
• Mol File: 1098100-86-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-cyano-4'-[2-n-propyl-4-methyl-6-methylcarboxylate-benzimidazole-1-ylmethyl]biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyano-4'-[2-n-propyl-4-methyl-6-methylcarboxylate-benzimidazole-1-ylmethyl]biphenyl(1098100-86-7)
• EPA Substance Registry System: 2-cyano-4'-[2-n-propyl-4-methyl-6-methylcarboxylate-benzimidazole-1-ylmethyl]biphenyl(1098100-86-7)

Safety Data

• Hazardous Substances Data: 1098100-86-7(Hazardous Substances Data)

Upstream product

• 152628-01-8 4-butyrylamino-3-methyl-5-nitro-benzoic acid methyl ester 
• 675882-71-0 3-methyl-4-butyrylamino-5-aminobenzoic acid methyl ester 
• 1206680-19-4 methyl 4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylate hydrochloride 
• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 152628-00-7 4-methyl-2-propyl-1H-benzimidazole-6-carboxylic acid methyl ester 

Downstream Products

• 1098100-87-8 2-cyano-4'-[2-n-propyl-4-methyl-6-carboxylate-benzimidazole-1-ylmethyl]biphenyl 
• 144702-27-2 4'-[[2-n-propyl-4-methyl-6-(1-methyl-benzimidazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-2-cyano-biphenyl 
• 1098100-91-4 4'-((N,7-dimethyl-N-(2-aminophenyl)-2-propyl-3H-benzo[d]imidazole-5-carboxamide-3-yI)-methyl)-biphenyl-2-nitrile 
• 1098100-88-9 7-methyl-N-(2-methylamino)-phenyl-2-propyl-3-(2'-cyano-4-ylmethylbiphenyl)-3H-benzimidazole-5-carboxamide 
• 144701-48-4 telmisatran 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF TELMISARTAN

The invention relates to processes for preparing telmisartan or a pharmaceutically acceptable salt thereof as well as to a process for preparing a telmisartan cyano intermediate. Moreover, the invention relates to a multilayer pharmaceutical tablet comprising (a) at least one first tablet layer comprising 1 to 50 wt. -% telmisartan or a pharmaceutically acceptable salt thereof by weight of the first tablet layer and (b) at least one second tablet layer comprising 1 to 50 wt.-% of a diuretic and 50 to 99 wt.-% of at least one filler by weight of the second tablet layer, wherein the combined weight of the diuretic and the at least one filler is at least 87 wt.-% by weight of the second tablet layer. The invention also relates to a process for the preparation of a multilayer pharmaceutical tablet.

PROCESS FOR PREPARING TELMISARTAN

Novel processes for preparing a telmisaitan nitrile intermediate (4'-[{2-n-propyl-4- methyI-6-f l-methyJbenzimidazol-2-yl)-benzimidazol- l -yl)-methyl]-biphenyl-2-nitrile) and further converting it to telmisaitan and/or salts thereof are disclosed.