109844-65-7

Basic information

• Product Name: N-(benzyl)-1H-imidazole-1-carboxamide
• Synonyms: N-(benzyl)-1H-imidazole-1-carboxamide
• CAS NO: 109844-65-7
• Molecular Weight: 201.228
• Mol File: 109844-65-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: N-(benzyl)-1H-imidazole-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzyl)-1H-imidazole-1-carboxamide(109844-65-7)
• EPA Substance Registry System: N-(benzyl)-1H-imidazole-1-carboxamide(109844-65-7)

Safety Data

• Hazardous Substances Data: 109844-65-7(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 5330-97-2 N-hydroxy-2-phenylacetamide 
• 530-62-1 1,1'-carbonyldiimidazole 
• 100-46-9 benzylamine 
• 3173-56-6 benzyl isothiocyanate 

Downstream Products

• 103-67-3 benzyl-methyl-amine 
• 73708-69-7 benzylcarbamoyl cyanide 
• 6343-54-0 N-benzylformamide 
• 25855-24-7 N-benzyl-N'-cyclohexylurea 
• 1215528-89-4 C₁₁H₁₆N₂O₂ 
• 1378233-16-9 C₁₄H₁₅N₃O₂ 
• 380221-68-1 C₃₇H₄₁N₉O₆ 

Relevant articles and documents

Catalytic Site-Selective Carbamoylation of Pyranosides

Carbamate-bearing carbohydrates contribute to the pharmacological properties of various natural glycosides. The catalytic site-selective carbamoylation of minimally protected pyranosides was achieved for the first time to bypass protection/deprotection sequences. 1-Carbamoylimidazoles were used as the carbamoylation reagents to circumvent the harmful and unstable phosgene and isocyanates. This borinic acid catalyzed transformation granted an expedient access to the tumor cell-binding carbamoylmannoside moiety of bleomycins and analogs in yields of 56% to 89%.

TRILOBINE DERIVATIVES AND THEIR USE THEREOF IN THE TREATMENT OF MALARIA

The present invention is in the field of therapeutic drugs to treat malaria. In particular, the invention provides trilobine derivatives per se, and trilobine derivatives for use in the treatment of malaria, for example drug-resistant malaria.

Solvent-Free Synthesis of Cyanoformamides from Carbamoyl Imidazoles

A straightforward and solvent-free synthesis of various secondary and tertiary cyanoformamides from carbamoyl imidazoles and TMSCN has been developed. Both cyclic and acyclic carbamoyl imidazoles react smoothly to form the relevant cyanoformamides in excellent yields, often within minutes.