109905-54-6

Basic information

• Product Name: (S)-3-hydroxycyclopentanone
• Synonyms: (S)-3-hydroxycyclopentanone
• CAS NO: 109905-54-6
• Molecular Weight: 100.117
• Mol File: 109905-54-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-3-hydroxycyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-hydroxycyclopentanone(109905-54-6)
• EPA Substance Registry System: (S)-3-hydroxycyclopentanone(109905-54-6)

Safety Data

• Hazardous Substances Data: 109905-54-6(Hazardous Substances Data)

Upstream product

• 16326-98-0 (+/-)-trans-1,3-cyclopentanediol 
• 930-30-3 cyclopent-2-enone 

Relevant articles and documents

SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES

Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

Enantioselective Michael addition of water

The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry.