109949-96-4

Basic information

• Product Name: N-(1-Dimethoxymethyl-propyl)-4-methyl-benzenesulfonamide
• Synonyms: N-(1-Dimethoxymethyl-propyl)-4-methyl-benzenesulfonamide
• CAS NO: 109949-96-4
• Molecular Weight: 287.38
• Mol File: 109949-96-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(1-Dimethoxymethyl-propyl)-4-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-Dimethoxymethyl-propyl)-4-methyl-benzenesulfonamide(109949-96-4)
• EPA Substance Registry System: N-(1-Dimethoxymethyl-propyl)-4-methyl-benzenesulfonamide(109949-96-4)

Safety Data

• Hazardous Substances Data: 109949-96-4(Hazardous Substances Data)

Upstream product

• 1907-65-9 N-butyl-4-toluenesulfonamide 
• 67-56-1 methanol 
• 124920-16-7 N-(1-methoxybutyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Electroorganic chemistry. 120. New patterns of anodic oxidation of amides. Synthesis of α-amino aldehyde acetals and pyrrolidines from amines

Anodic oxidation of N-alkyltosylamides 1 in methanol containing KX (X = Br, I) gave two types of products, α-(tosylamino) aldehyde acetals 2 and pyrrolidine derivatives 3, and each of the products could selectively be formed by modifying the reaction conditions when the alkyl group on the nitrogen of 1 was not branched at its α-position. Namely, anodic oxidation ot N-(α-unbranched alkyl)tosylamides 1a-g in methanol containing NaOMe and KI at -10°C followed by further anodic oxidation at 25°C afforded 2 in good yields, while that of 1 in a two-layer system consisting of cyclohexane and water containing KOH and KBr under heating yielded solely 3. On the other hand, N-(α-branched alkyl)tosylamides 1h-j gave always 3. Two types of reaction routes leading to each of the products were proposed.