109988-88-7

Basic information

• Product Name: 12-Desvinyl-12-cyclopropyl-22-O-tosyl-pleuromutilin
• CAS NO: 109988-88-7
• Molecular Weight: 546.725
• Mol File: 109988-88-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12-Desvinyl-12-cyclopropyl-22-O-tosyl-pleuromutilin(CAS DataBase Reference)
• NIST Chemistry Reference: 12-Desvinyl-12-cyclopropyl-22-O-tosyl-pleuromutilin(109988-88-7)
• EPA Substance Registry System: 12-Desvinyl-12-cyclopropyl-22-O-tosyl-pleuromutilin(109988-88-7)

Safety Data

• Hazardous Substances Data: 109988-88-7(Hazardous Substances Data)

Upstream product

• 75-11-6 diiodomethane 
• 31716-01-5 Pleuromutilin-22-O-tosylat 

Relevant articles and documents

Inversion of Configuration of the Vinylgroup at Carbon 12 by Reversible Retro-En-Cleavage

The reaction of pleuromutilin-22-O-tosylat(2) with EtZnI afforded a mixture of the 12-epimeric compounds 2 and 3.A reversible retro-en-reaction of the homoallylic system is discussed as a possible mechanistic pathway.The structure assignment is based on 1H- and 13C-NMR spectroscopic data. - Keywords: Pleuromutilin; Inversion of configuration; Reversible retro-en-cleavage; Simmons-Smith-reaction; Type I-"metallo-en"-reaction