110-70-3Relevant articles and documents
Identifying the roles of amino acids, alcohols and 1,2-diamines as mediators in coupling of haloarenes to arenes
Zhou, Shengze,Doni, Eswararao,Anderson, Greg M.,Kane, Ryan G.,Macdougall, Scott W.,Ironmonger, Victoria M.,Tuttle, Tell,Murphy, John A.
, p. 17818 - 17826 (2014)
Coupling of haloarenes to arenes has been facilitated by a diverse range of organic additives in the presence of KOtBu or NaOtBu since the first report in 2008. Very recently, we showed that the reactivity of some of these additives (e.g., compounds 6 and 7) could be explained by the formation of organic electron donors in situ, but the role of other additives was not addressed. The simplest of these, alcohols, including 1,2-diols, 1,2-diamines, and amino acids are the most intriguing, and we now report experiments that support their roles as precursors of organic electron donors, underlining the importance of this mode of initiation in these coupling reactions.
New method for preparing N,N'-dimethylethylenediamine and N,N'-dimethyl-1,3-propanediamine
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Paragraph 0009-0014, (2019/10/01)
The present invention relates to a new method for preparing N,N'-dimethylethylenediamine and N,N'-dimethyl-1,3-propanediamine, wherein 1,3-dimethyl-2-imidazolidinone or 1,3-dimethyl-tetrahydro-2-pyrimidone is used as a raw material, a suitable alkali is added, and a heating ring-opening reaction is perform to prepare N,N'-dimethylethylenediamine and N,N'-dimethyl-1,3-propanediamine. In the prior art, the conventional method performs alkylation by using the amine as the raw material to generate more by-products. According to the present invention, the method completely avoids the problem in theprior art, has characteristics of simple operation, high yield, less three-waste and high product purity, and is suitable for industrial production.
Nitric oxide reactivity of copper(ii) complexes of bidentate amine ligands: Effect of substitution on ligand nitrosation
Sarma, Moushumi,Mondal, Biplab
experimental part, p. 2927 - 2934 (2012/04/10)
Three copper(ii) complexes with bidentate ligands L1, L 2 and L3 [L1, N,N/- dimethylethylenediamine; L2, N,N/-diethylethylenediamine and L3, N,N/-diisobutylethylenediamine], respectively, were synthesized as their perchlorate salts. The single crystal structures for all the complexes were determined. The nitric oxide reactivity of the complexes was studied in acetonitrile solvent. The formation of thermally unstable [CuII-NO] intermediate on reaction of the complexes with nitric oxide in acetonitrile solution was observed prior to the reduction of copper(ii) centres to copper(i). The reduction was found to result with a simultaneous mono- and di-nitrosation at the secondary amine sites of the ligand. All the nitrosation products were isolated and characterized. The ratio of the yield of mono- and di-nitrosation product was found to be dependent on the N-substitution present in the ligand framework.