110072-15-6Relevant articles and documents
11-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions
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, (2008/06/13)
The present invention is concerned with novel 11-methylene-oestr-15-enes of the formula: STR1 wherein R 1 =H or acyl with 1-18 C-atoms, preferably H,R 2 =ethinyl, vinyl, chloroethinyl, allyl or propinyl; ethinyl being preferred, andR 3 =O or H 2, preferably O.Further the present invention is concerned with processes for the preparation of the above compounds and with pharmaceutical compositions comprising these compounds. The compounds possess powerful gestagenic properties and only slight androgenic side-effects.