110079-40-8

Basic information

• Product Name: N-isopropylbenzyl-α,α-d2-amine
• Synonyms: N-isopropylbenzyl-α,α-d2-amine
• CAS NO: 110079-40-8
• Molecular Weight: 151.22
• Mol File: 110079-40-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-isopropylbenzyl-α,α-d2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-isopropylbenzyl-α,α-d2-amine(110079-40-8)
• EPA Substance Registry System: N-isopropylbenzyl-α,α-d2-amine(110079-40-8)

Safety Data

• Hazardous Substances Data: 110079-40-8(Hazardous Substances Data)

Upstream product

• 5440-69-7 N-isopropylbenzamide 

Downstream Products

• 141334-82-9 1-isopropyl-2,3,5-triphenylpyrrole-4-d 
• 144500-98-1 N-isopropyl-N-methyl-d3-benzyl-α,α-d2-amine 

Relevant articles and documents

The Reactions of Monoalkylthio- or Monoarylthio-Substituted Cyclopropenium Salt with Nitrogen Nucleophiles: Formation of Polyfunctionally Substituted Pyrroles or Pyrazoles

The reactions of monoalkylthio- or monoarylthio-substituted cyclopropenium salt (1) with a number of secondary amines were studied.The amines, such as N-methylaniline, yielded indenes, whereas N-alkyl- or N-arylbenzylamines gave 1-alkyl or 1-aryl-2-phenyl

Reactions of N-Chlorobenzylalkylamines with Sodium Methoxide in Methanol. Steric Effects in Elimination Reactions

Reactions of N-chlorobenzylalkylamines in which the alkyl group is Me, Et, i-Pr, t-Bu, and sec-Bu with MeONa-MeOH have been investigated kinetically.The eliminations are quantitative and regiospecific, producing only benzylidenealkylamines.The reactions are first order in base and first order in substrate, and an E2 mechanism is evident.The relative rates of elimination at 25 deg C are 1/0.5/0.3/0.2/0.01 for Me/Et/i-Pr/sec-Bu/t-Bu alkyl substituents, respectively.The results are attributed to repulsive interaction between the alkyl group and the base in the transition state.Hammett ρ and kH/kD values decreased, but the ΔH(excit.) and ΔS(excit.) values increased with bulkier alkyl substituents.Changes in the transition-state parameters with the substrate steric effect are interpreted with variation in structure of the imine-forming transition states.