110096-37-2

Basic information

• Product Name: Bicyclo[3.2.0]hepten-6-one, 7,7-dichloro-
• CAS NO: 110096-37-2
• Molecular Formula: C7H6Cl2O
• Mol File: 110096-37-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Bicyclo[3.2.0]hepten-6-one, 7,7-dichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[3.2.0]hepten-6-one, 7,7-dichloro-(110096-37-2)
• EPA Substance Registry System: Bicyclo[3.2.0]hepten-6-one, 7,7-dichloro-(110096-37-2)

Safety Data

• Hazardous Substances Data: 110096-37-2(Hazardous Substances Data)

Upstream product

• 63320-25-2 7,7-dichloro-4β-trimethylsilylbicyclo<3.2.0>hept-2-en-6-one 

Relevant articles and documents

PROSTANOIDS. LII. (+/-)-7,7-DICHLORO-4β-TRIMETHYLSILYLBICYCLOHEPT-3-EN-6-ONE IN THE SYNTHESIS OF PROSTANOIDS. RACEMIC CARBACYCLIN

The products from the Prins reaction of formaldehyde and (+/-)-7,7-dichloro-4β-trimethylsilylbicyclohept-3-en-6-one were isolated and characterized.The optimum conditions were found for the production of the isomeric 2β-acetoxy-6,6(7,7)-dichlorobicyclohept-3-en-7(6)-ones and 2β-acetoxymethyl-3α-acetoxy-6,6(7,7)-dichlorobicyclohept-3-en-7(6)-ones and also (1R,2S,5R,6S,10R)-3,3-dichloro-4-oxo-10-hydroxy(acetoxy)-8-oxatricyclo2,5>undecanes, suitable for the subsequent synthesis of modified prostanoids.An effective scheme for the synthesis of (+/-)-carbacyclin was worked out on the basis of the monoacetates of a series of bicycloheptenones through the corresponding 2β-acetoxymethyl-3α-acetoxybicyclooctan-7-ones.