110117-34-5

Basic information

• Product Name: 1H-Inden-1-one, 2,3-dihydro-2-[(3-methoxyphenyl)methylene]-
• CAS NO: 110117-34-5
• Molecular Formula: C17H14O2
• Molecular Weight: 250.297
• Mol File: 110117-34-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Inden-1-one, 2,3-dihydro-2-[(3-methoxyphenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Inden-1-one, 2,3-dihydro-2-[(3-methoxyphenyl)methylene]-(110117-34-5)
• EPA Substance Registry System: 1H-Inden-1-one, 2,3-dihydro-2-[(3-methoxyphenyl)methylene]-(110117-34-5)

Safety Data

• Hazardous Substances Data: 110117-34-5(Hazardous Substances Data)

Upstream product

• 83-33-0 inden-1-one 
• 591-31-1 3-methoxy-benzaldehyde 
• 6971-51-3 3-methoxybenzyl alcohol 

Downstream Products

• 13579-03-8 2.2-Bis-(m-methoxy-benzyl)-1-indanon 
• 110117-37-8 4-(3-Methoxy-phenyl)-5H-indeno[1,2-d]pyrimidin-2-ylamine 

Relevant articles and documents

Green, rapid, and highly efficient syntheses of α,α′-bis[(aryl or allyl)idene]cycloalkanones and 2-[(aryl or allyl)idene]-1-indanones as potentially biologic compounds via solvent-free microwave-assisted Claisen–Schmidt condensation catalyzed by MoCl5

A new, green, and highly efficient protocol for the expeditious preparation of some α,α′-bis[(aryl or allyl)idene]cycloalkanones and 2-[(aryl or allyl)idene]-1-indanones via a simple microwave-assisted Claisen–Schmidt condensation reaction catalyzed by MoCl5 was successfully developed. Outstanding features of the current methodology include the use of solvent-free conditions, simple operation, use of a very inexpensive and available catalyst, low catalyst loading, short reaction times, high yields of the pure products, no harmful by-products, easy workup, and also the applicability of microwave irradiation as a clean source of energy. Furthermore, a gram-scale reaction was successfully conducted, proving the scalability of this current Claisen–Schmidt condensation reaction.

Michael addition of malononitrile to indenones: Synthesis and characterization of 2-(1-oxo-2,3-dihydro-1H-inden-2-yl) (aryl)(methyl)malononitrile derivatives

Indanones 3 were prepared from the reaction of indanone (1) with corresponding benzaldehyde derivatives 2, as described in the literature. Then, indenones 3 were subjected to KOtBu-catalyzed Michael addition with malononitrile to give a mixture of diaster

Evaluation of silica-H2SO4 as an efficient heterogeneous catalyst for the synthesis of chalcones

We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the targeted compounds in very good yield compared to base catalyzed solvent free conditions as well as acid or base catalyzed refluxing conditions.