110130-88-6

Basic information

• Product Name: (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID
• Synonyms: ATAIA;4-THIAZOLEACETIC ACID, ALPHA-[(ACETYLOXY)IMINO]-2-AMINO-, (Z)-;(Z)-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID;ATAIA:( Z )-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID;( Z )-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID (ATAIA);4-THIAZOLEACETICACID,A-[(ACETYLOXY)IMINO]-2-AMINO;(Z)-2-(AcetoxyiMino)-2-(2-aMinothiazol-4-yl)acetic acid
• CAS NO: 110130-88-6
• Molecular Formula: C7H7N3O4S
• Molecular Weight: 229.21
• Mol File: 110130-88-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 469.468 °C at 760 mmHg
• Flash Point: 237.726 °C
• Appearance: /
• Density: 1.698 g/cm³
• Vapor Pressure: 1.29E-09mmHg at 25°C
• Refractive Index: 1.694
• PKA: 2.23±0.10(Predicted)
• CAS DataBase Reference: (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID(110130-88-6)
• EPA Substance Registry System: (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-ACETYLOXYIMINOACETIC ACID(110130-88-6)

Safety Data

• Hazardous Substances Data: 110130-88-6(Hazardous Substances Data)

Usage

General Description

"(Z)-2-(2-aminthiazol-4-yl)-2-acetyloxyiminoacetic acid" is a chemical compound that contains a thiazole ring and an acetyloxyimino group. It is a derivative of the amino acid glycine and has potential applications in medicine and biochemistry. The compound has been studied for its biological activities, including antibacterial and antioxidant properties. Its structure and properties make it a potentially valuable chemical for drug development and understanding biochemical processes.

InChI:InChI=1/C7H7N3O4S/c1-3(11)14-10-5(6(12)13)4-2-15-7(8)9-4/h2H,1H3,(H2,8,9)(H,12,13)/b10-5+

Upstream product

• 108-24-7 acetic anhydride 
• 120570-48-1 syn-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)-acetic acid 
• 497-19-8 sodium carbonate 

Downstream Products

• 104797-47-9 S-2-benzothiazolyl (Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyimino thioacetate 
• 946573-41-7 cefdinir lactone 

Relevant articles and documents

Preparation method of aminothiazole acetyloxime acid with controllable particle size

The invention relates to a preparation method of aminothiazole acetyloxime acid with a controllable particle size, and belongs to the technical field of chemical pharmacy. The preparation method comprises the following steps: ahydrolysis step: hydrolyzing ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate serving as a raw material to generate a compound 1; an acylation step: dropwisely adding an acylating agent into the system to perform acylation reaction to obtain a compound 2; and a crystallization step: adding activated carbon into the reaction system for decolorization, then dropwise adding an acidic solution into the system at different temperatures to control the pH value of the system, and after the solid is separated out, carrying out centrifugal drying to obtain a compound 3 with controllable particle size. According to the method, by controlling different acid liquor adding temperatures, the particle size of the prepared aminothiazole acetyloxime acid is controllable; and the technological process is simple to operate and suitable for industrial production.

PROCESS FOR PRODUCING ANHYDRIDE OF AMINOTHIAZOLE DERIVATIVE

This invention provides a novel industrial process for preparation of an anhydride of 2-(2-aminothiazole-4-yl)-2-hydroxy compound.