110444-43-4

Basic information

• Product Name: Butanoic acid, 2-chloro-3-hydroxy-, ethyl ester, (2R,3S)-
• CAS NO: 110444-43-4
• Molecular Formula: C6H11ClO3
• Molecular Weight: 166.605
• Mol File: 110444-43-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-chloro-3-hydroxy-, ethyl ester, (2R,3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-chloro-3-hydroxy-, ethyl ester, (2R,3S)-(110444-43-4)
• EPA Substance Registry System: Butanoic acid, 2-chloro-3-hydroxy-, ethyl ester, (2R,3S)-(110444-43-4)

Safety Data

• Hazardous Substances Data: 110444-43-4(Hazardous Substances Data)

Upstream product

• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 

Downstream Products

• 821783-49-7 ethyl (2R,3S)-2-(4-chlorophenoxy)-3-hydroxybutanoate 
• 821783-51-1 ethyl (2S,3S)-2-(4-chlorophenoxy)-3-hydroxybutanoate 
• 110508-08-2 Ethyl (2S,3S)-2,3-epoxybutanoate 
• 25834-24-6 ethyl (2R,3S)-3-methyloxirane-2-carboxilate 
• 19780-35-9 ethyl (2R,3S)- and (2S,3S)-2,3-epoxybutanoate 

Relevant articles and documents

THE PRODUCT OF BAKER'S YEAST REDUCTION OF ETHYL 2-CHLORO-3-OXOBUTANOATE AS A PRECURSOR OF THE 1-ETHOXYCARBONYL 2(S)-HYDROXYPROPYL RADICAL

Baker's yeast treatment of ethyl 2-chloro-3-oxobutanoate 1, diethyl 2-acetylmalonate 2 and ethyl 2-cyano-3-oxobutanoate 3 was effected in order to obtain enantiomerically enriched compounds.In contrast to the reaction of 2 and 3, efficient diastereo- and enantioselective reduction of 1 provided ethyl 2(R)-chloro-3(S)-hydroxybutanoate.This product was used as precursor of the 1-ethoxycarbonyl-2(S)-hydroxypropyl radical and the diastereoselectivity of the addition of this intermediate to alkenes was studied.